In Situ Hybridization with Riboprobes: An Overview for Veterinary Pathologists
- 1Department of Veterinary Pathology, College of Veterinary Medicine, University of Georgia, Athens, GA
- Department of Veterinary Pathology, College of Veterinary Medicine, D.W. Brooks Drive, University of Georgia, Athens, GA 30602–7388 (USA).
Abstract
In situ hybridization using nonradioactively-labeled RNA probes is a technique that combines understanding of basic molecular biology and histopathologic interpretation. Recombinant or PCR technology can be used to produce probes that hybridize with a wide variety of cellular genes and infectious agents. Hybridization conditions can be optimized for each probe/target combination.
- © 1998 American College of Veterinary Pathologists
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